Common Scenarios of Cleanroom Air Purification in Biopharma, Electronics, and Research Labs
In precision instrument laboratories, a single particle of dust or a trace of microbial contamination can nullify weeks of meticulous work. Clean air is never just a background feature—it is the lifeline that determines the success or failure of experiments. This article provides a comprehensive overview of common cleanroom air filtration applications in laboratories.
1. Biopharmaceutical Applications
01. Biosafety Laboratories (BSL-1 to BSL-4)
- Filtration Requirements: Negative pressure environment to prevent aerosol spread; BSL-3/BSL-4 labs require dual HEPA filtration and biosafety cabinets.
- Application Scenarios: Virus research, vaccine development, high-pathogenicity microorganism experiments.
02. Sterile Pharmaceutical and Medical Device Laboratories
- Filtration Requirements: Class 10,000–100 cleanrooms to prevent particulate and microbial contamination.
- Application Scenarios: Intravenous drug preparation rooms, sterile testing laboratories.
03. Cell Culture and Genetic Engineering Laboratories
- Filtration Requirements: Class 1,000 cleanrooms; laminar flow hoods or biosafety cabinets ensure aseptic operation.
- Application Scenarios: Stem cell culture, gene sequencing sample preparation, monoclonal antibody production.
2. Precision Manufacturing and Testing
01. Semiconductor and Microelectronics Laboratories
- Filtration Requirements: Class 100 ultra-clean environment, 0.1 μm particle removal; temperature/humidity fluctuations ≤ ±0.5°C.
- Key Technologies: ULPA filters with vertical unidirectional airflow.
- Application Scenarios: Nanoscale photoresist coating, wafer defect inspection, high-precision chip packaging.
02. Optical Components and Aerospace Component Laboratories
- Filtration Requirements: Class 1,000–10,000 cleanrooms; prevent dust affecting calibration or synthesis.
- Application Scenarios: Satellite laser gyroscope calibration, aerospace composite curing, high-precision optical lens coating.
3. Chemical and Material Laboratories
01. Cosmetic Testing Laboratories
- Filtration Requirements: Class 100,000–300,000 cleanrooms to control microbial and particulate contamination.
- Special Design: Sequential workflow: changing room → air shower → cleanroom.
- Application Scenarios: Sterile filling of serums, facial mask microbial limit testing, stability testing of skincare products.
02. High-Precision Material Synthesis Labs
- Filtration Requirements: Class 10,000 cleanrooms; explosion-proof purification equipment recommended.
- Application Scenarios: Nanocatalyst synthesis, lithium battery separator development, high-purity specialty gas production.
4. Animal Research Laboratories (SPF Grade)
- Filtration Requirements: Class 10,000 cleanrooms; maintain directional air pressure gradient to control pathogens.
- Application Scenarios: Preclinical drug toxicology, gene knockout animal breeding, infectious disease research.
Laboratory Air Purification: Supply and Exhaust
Laboratory air purification is managed on two fronts:
- Supply Air: Protects laboratory spaces and experimental operations, ensuring successful results.
- Exhaust Air: Protects non-experimental areas and external environment, meeting regulatory emission standards.
Filters for Laboratory HVAC Systems
Pre- and Medium-Efficiency Filters: Capture large particles, protect high-efficiency filters, and extend service life.
High-Efficiency Filters: Installed at supply air terminals; filters 0.3 μm particles with H14 efficiency of 99.995%.
High-Efficiency Supply Air Terminals
- Filtration Efficiency: H14, 99.995% @ MPPS
- Convenience: Replaceable filter design
- Sealing Options: Mechanical, liquid seal, or dual-seal
- Optional Features: PAO testing for in-situ verification
- Compatibility: Suitable for labs and pharmaceutical cleanrooms
Smart High-Efficiency Supply Terminals
- Constant Airflow: Maintains set airflow despite filter resistance increase
- Intelligent Adjustment: Automatic damper modulation to keep airflow steady
- Remote Control: Wired/digital transmission for local or remote operation
- Integrated Functions: Energy-saving, mode switching, reset capability, interference-free
Clean Transfer Windows
- Filtration: H14 liquid-sealed HEPA filter with differential pressure gauge
- Durability & Hygiene: SUS304 construction, rounded design, corrosion-resistant
- Safety Interlock: Dual-sided door interlocks prevent cross-contamination
Clean Benches
- Ergonomic Operation: 10° tilt design
- Sealing Reliability: Negative-pressure sealing prevents leakage
- Stable Environment: Glass front panel maintains clean conditions
- Window Monitoring: Alarm triggers if front sash is out of position
Chemical Filters
- Adsorption Filtration: Removes formaldehyde and VOCs, controls odors
- Functional Expansion: Additives in activated carbon target specific chemicals
- Standard End-of-Line Equipment: Used for animal facility exhaust, fume hood exhaust, etc.
Brand Introduction
E-FILT provides advanced cleanroom air filtration solutions for laboratories, pharmaceutical plants, electronics manufacturers, and chemical facilities. Our expertise in HEPA filtration, smart airflow terminals, and customized cleanroom systems ensures reliable contamination control, operational efficiency, and compliance with global standards. From biological research to high-precision manufacturing and chemical synthesis, our solutions deliver clean, safe, and controlled environments for critical operations.
